Ameer Taha

2017 Hellman Fellow

Assistant Professor, Food Science & Technology
UC Davis

Project Title: A new lipid signaling pathway that facilitates brain repair

Project Description:

In many neurological disorders, inflammation steers out of control because repair pathways are impaired, resulting in neurodegeneration and disease progression. Taha recently discovered that during brain inflammation, repair molecules enzymatically derived from dietary polyunsaturated fatty acids become actively ‘trapped’ in phospholipid structures that make up brain cells, rendering them inactive. To facilitate brain repair, Taha proposes to discover and inhibit the enzyme that traps these repair molecules in brain phospholipids. If successful, this research will lead to novel therapies that cure neurodegenerative brain disorders by stimulating brain repair.